The temblors hit on Thursday morning, were felt far and wide and even rattled the Iraqi capital of Baghdad.
According to Iran's state TV, the western province of Kermanshah was hit by a strong natural disaster. Earthquakes at magnitude 5 can cause considerable damage.
Also, according to the USGS, the earthquakes hit at a depth of about six miles.
ISNA said the five injured were in Kermanshah province, and state television reported no major damage.
Randy Baldwin, a geophysicist with the USGS' National Earthquake Information Center in Golden, Colorado, said the earthquakes all appeared to be aftershocks from the November temblor. Many people are still living in temporary homes and tents. "If there was a stressed fault that's ready to move, they happen like that until the stresses are relieved, so it's not too unusual". Sarpol-e Zahab suffered half of the temblor's casualties. On Nov. 12, on the Iran-Iraq border there were two stronger quakes with magnitude 7.2 and 7.3 at the Richter.
There were no immediate reports of injuries or damage.
Iran sits on major seismic fault lines and is prone to frequent earthquakes.
In 2003, a magnitude 6.6 quake in the province of Kerman flattened the historic city of Bam, killing more than 26,000 people.
An natural disaster of the magnitude 4.1 on the Richter scale has jolted Iran's southeastern province of Kerman.
Besides, a 5.4-magnitude quake jolted Zarneh region in Iran's Ilam province.