Prior to the ceremony, most stars wore black on the red carpet, as a mark of solidarity with victims of sexual assault and harassment.
Also nominated from the film were Greta Gerwig for Best Screenplay and Laurie Metcalf for Best Supporting Actress, but they lost out to Three Billboards Outside Ebbing Missouri's Martin McDonagh and I, Tonya's Allison Janney, respectively.
"This year, we became the story", Oprah Winfrey said in a rousing speech while accepting the annual lifetime achievement award.
"But their time is up", she added, earning a standing ovation."I want all the girls watching here and now to know that a new day is on the horizon", she added. Presenting the Best Actor in a Drama award, Geena Davis said that the victor would give "half of their salary back so that women can make more than them".
"Big Little Lies" from the television world and "Three Billboards Outside Ebbing, Missouri" from the movie universe won four awards each at the 75th Golden Globe Awards, which saw Indian American actor-comedian Aziz Ansari make history for Asians. Critics praised the acting, particularly Frances McDormand's effortlessly foul mouthed character in a thrift-store-gold mechanic's jumpsuit and Sam Rockwell's conflicted cop.
James Franco won the comedy actor award for his cult movie homage "The Disaster Artist", also from A24.
Sterling K. Brown was the only television network actor to take home a Globe, earning the prize for drama series actor for his work in NBC's "This is Us".
The show's star, Rachel Brosnahan, won her first career Golden Globe for lead actress in a comedy.
Skarsgard hailed the cast of "extraordinarily talented women" in the show, but he singled out Kidman.
Laura Dern, a supporting actress victor for "Big Little Lies", said: "May we teach our children that speaking out without retribution is our culture's new north star".
The Hulu drama "The Handmaid's Tale" snagged the Best Drama award in the first hour of the broadcast.
After reading a quote from Atwood, she told the audience: "We no longer live in the gaps... we are the story in print and we are writing the story ourselves".