And speaking after the game, the 30-year-old confirmed his intention to stay and fight for his place at Emirates Stadium.
Fredrik Ljungberg marked his debut with the final goal in a 3-0 win over Manchester United in September 1998, while Emmanuel Adebayor got off on the right foot away to Birmingham City in February 2006.
Leicester have since levelled the scores to 1-1 with Shinji Okazaki scoring just 160 seconds after Arsenal took the lead.
Players were given a chance to breathe for a bit until Leicester struck again 20 minutes later.
"With Lacazette, it is simple", the French tactician said, as quoted by FourFourTwo.
"He came out and made a statement which we are all aware of but while he trains and plays and is professional the way he is, he will be considered for selection".
Everton have been dealt a bitter blow in their attempts to sign Olivier Giroud after the striker confirmed he is not leaving Arsenal this summer. He doesn't want to leave and I'm happy he wants to stay.
Giroud also spoke to reporters, saying he's hoping for a bigger role in the future after coming on as a substitute on Friday: "That's a nice start, but obviously I prefer to be on the pitch".
Tonight's victor was his 70th Premier League goal - coming at the start of his sixth season. "I don't know whether it was lack of concentration or game management".
"We know defensively we can do better but overall we produced a top-quality game".
"And you could see that this team has quality and is used to playing together, but [we had] 70 per cent possession with 27 shots on goal".