This year, they will have to ensure that they bring back an aura of invincibility to Old Trafford and do not drop points, especially at home.
Romelu Lukaku is this summer's star signing to help fire United to the top of the table but manager Mourinho reckons everything has changed in the past 12 months. With the new signings, Mourinho could line his team in a variety of ways but a 4-3-3 or a 4-2-3-1 looks set to be the preferred formation. I was thinking, three transfer windows, I need that. We are much better organised at every level.
Newcastle will feature in the Premier League this season after winning automatic promotion from the Championship at the end of the 2016-17 campaign. I will just go with everything.
"We have a good squad - a good squad also in numbers".
"Arsenal and Everton are in the Europa League and they have to play Thursdays".
"In my initial analysis from January and through the months I was thinking of four players but I'm not a hard person to work with in spite of if you make it look different", said Mourinho, ahead of United's Premier League opener against West Ham, live on Sky Sports Premier League on Sunday. Some of these are tricky fixtures, but it's against teams like these that United struggled last season.
"My dedication to my job is always the maximum even more than when I started". I want, I want!
All eyes will be on Lukaku today as United's £75million man makes his debut against the Hammers today.
He said: "When I joined Man United past year, I thought we needed a kind of Matic".
Manchester United begins its league campaign on Sunday, hosting West Ham. It's not just for his qualities but my relation with him and the way I know him'.
The Hammers finished 11th in the Premier League previous year, as they settled into their first campaign at the London Stadium, recovering well after a very shaky start at the new ground. He's a player who gives me what I like, which is consistency.
"I think everybody is in Europe".
Asked if Manchester United was his team now, he didn't hesitate to agree.
He said: "To buy lots of good players is important". That is normal, but that is not enough.
It was a classic Mourinho move - the image was splashed on the front pages of most newspapers and websites giving readers a lingering sense that this was a team that had tasted a lot of success.
"But he's still a very good player to sit in front of the back four, do the simple things, pass the ball - he's good at what he does".